UV irradiation of polar cells of drosophila melanogaster embryos

Autor: C. Prudhommeau, J. Proust
Rok vydání: 1974
Předmět:
Zdroj: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 23:63-66
ISSN: 0027-5107
DOI: 10.1016/0027-5107(74)90161-4
Popis: Polar cells of female embryos heterozygous for the genetic markers st in ri were UV irradiated. The effect of UV irradiation on the meiotic recombination within the st-ri segment was analysed. In individuals that contained this chromosome segment in its normal position, UV increased the rate of meiotic recombination. If this segment were separated from the centromeric heterochromatin and translocated on the left arm of chromosome II, UV did not influence meiotic recombination to a significant extent. On the other hand, in non-irradiated controls the individuals containing the translocated segment showed an increased rate of recombination within the segment compared with individuals having the segment in its normal position. These results can be explained by Suzuki's hypothesis according to which a heterocatalytic activity of heterochromatin shows an antagonism to meiotic recombination. UV seems to interfere with this antagonism indirectly via induction of physiological damage.
Databáze: OpenAIRE