Targeted Radiation Therapy Can Treat Myxomatous Cerebral Aneurysms
| Autor: | Nader Pouratian, Lucido Luciano Ponce Mejia, Viktor Szeder, Yinn Ooi, Kasra Khatibi, Naoki Kaneko, Tania Kaprealian, Nestor R Gonzalez |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Chemotherapy business.industry medicine.medical_treatment Myxoma Fusiform Aneurysm Clipping (medicine) medicine.disease Radiosurgery Radiation therapy Natural history 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis cardiovascular system Medicine Surgery cardiovascular diseases Neurology (clinical) Clinical efficacy Radiology business 030217 neurology & neurosurgery |
| Zdroj: | World Neurosurgery. 143:332-335 |
| ISSN: | 1878-8750 |
| DOI: | 10.1016/j.wneu.2020.08.022 |
| Popis: | Background Neoplastic cerebral aneurysms are rare presentations of cardiac myxomas. The natural history of such aneurysms is not well understood, and the optimal treatment strategy remains unclear. Clipping and coiling are effective, although can carry significant morbidity. Chemotherapy and radiation can theoretically be effective, although their clinical efficacy remains to be proven. Case Description Here we describe a patient with cardiac myxoma presenting with multiple progressively fusiform aneurysms. These aneurysms were noted to be growing during conservative monitoring given the eloquent location. Subsequently, the patient underwent multiple sessions of targeted radiation therapy, which lead to obliteration, shrinkage, or halting in growth of these aneurysms. Conclusions Low-dose targeted radiation therapy can be safe and effective in treatment of neoplastic myxomatous aneurysms. |
| Databáze: | OpenAIRE |
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