Oral ingestion of colostrum alters intestinal transforming growth factor-beta receptor intensity in newborn pigs
| Autor: | Yuanqiang Zhang, Ruo-Jun Xu, T. Wang, Jie Mei, Per T. Sangild |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
General Veterinary biology animal diseases Crypt Mammary gland food and beverages Transforming growth factor beta fluids and secretions Endocrinology medicine.anatomical_structure Infant formula Internal medicine medicine biology.protein Colostrum Animal Science and Zoology Secretion Receptor Transforming growth factor |
| Zdroj: | Livestock Science. 105:214-222 |
| ISSN: | 1871-1413 |
| DOI: | 10.1016/j.livsci.2006.06.017 |
| Popis: | Mammary gland secretion contains numerous bioactive compounds including transforming growth factor-beta (TGF-β). The concentrations of such bioactive compounds are usually much higher in colostrum compared with those in mature milk. To investigate possible effects of colostrum-borne TGF-β on the suckling animal, newborn piglets were naturally suckled or bottle-fed with porcine colostrum, bovine colostrum, porcine milk, infant formula or water for 24 h and intestinal TGF-β receptor intensity was assessed using an immunohistochemical staining technique in combination with computerized image analysis. The intestinal structure was also analyzed by morphometric analysis technique. It was observed that newborn pigs naturally suckled or bottle-fed with porcine or bovine colostrum had significantly greater intestinal villous height and crypt depth when compared with those fed with porcine milk, infant formula or water ( p p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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