Imagerie des tumeurs stromales digestives
| Autor: | Lounis Hamzi, M Pocard, Mourad Boudiaf, I Idy-Peretti, Yann Fargeaudou, F Duchat, P. Soyer, Roland Rymer, J Nemeth, Xavier Dray, D Bensimhon, S Martin-Grivaud |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty Radiological and Ultrasound Technology medicine.diagnostic_test GiST business.industry Cancer Imatinib medicine.disease Interstitial cell of Cajal symbols.namesake medicine.anatomical_structure Imatinib mesylate Positron emission tomography Biopsy medicine symbols Radiology Nuclear Medicine and imaging business Lymph node medicine.drug |
| Zdroj: | Journal de Radiologie. 90:469-480 |
| ISSN: | 0221-0363 |
| DOI: | 10.1016/s0221-0363(09)74006-5 |
| Popis: | Gastrointestinal stromal tumors (GIST) arising from interstitial cells of Cajal, represent the first type of solid tumor, which is very sensitive to a specific molecularly targeted tyrosine kinase receptor blocker (i. e., imatinib). On CT, which is considered as the reference technique, GISTs typically present as large, well-delineated, heterogeneous and sometimes exophytic masses. In contrast with the absence of lymph node involvement, hepatic metastasis as well as mesenteric involvement can be observed. MR-enteroclysis is indicated to investigate the local extent of the disease in specific cases whereas MR imaging is used to detect hepatic metastasis. Because of a specific treatment, contrast-enhanced imaging is needed for the follow-up of treated tumors. Evaluation of tumor response to treatment is best assessed with CT which still remains the reference imaging technique whereas FDG-PET imaging is used in specific cases. |
| Databáze: | OpenAIRE |
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