Escherichia coli 0157:H7 and the Hemolytic Uremic Syndrome: Importance of Early Cultures in Establishing the Etiology

Autor:	Dennis L. Christie, Carla R. Clausen, Phillip I. Tarr, Sandra L. Watkins, Robert O. Hickman, Marguerite A. Neill
Rok vydání:	1990
Předmět:	medicine.medical_specialty Biology medicine.disease_cause biology.organism_classification Enterobacteriaceae Microbiology Diarrhea fluids and secretions Infectious Diseases Epidemiology medicine Etiology Immunology and Allergy Bloody diarrhea medicine.symptom Escherichia coli Pathogen Feces
Zdroj:	Journal of Infectious Diseases. 162:553-556
ISSN:	1537-6613 0022-1899
DOI:	10.1093/infdis/162.2.553
Popis:	Fifty-two patients were studied prospectively to determine the etiology of postdiarrheal hemolytic uremic syndrome (HUS). Escherichia coli O157:H7 was isolated from 33 patients (63.4%). If stool obtained within 2 days of the onset of diarrhea was cultured for E. coli O157:H7, the recovery rate was 100%. This rate decreased to 91.7% and 33.3% if stool was cultured for this pathogen 3-6 or greater than or equal to 7 days, respectively, after diarrhea began. The culture-positive group was more likely to have had bloody diarrhea and fecal leukocytes and to have received transfusions than the culture-negative group but was otherwise similar in clinical characteristics. E. coli O157:H7 is the predominant pathogen associated with HUS in western Washington. Recovery of this pathogen is highly dependent on obtaining stool cultures within 6 days of onset of diarrhea.
Databáze:	OpenAIRE
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