Zn(OTf)2-Mediated Expeditious and Solvent-Free Synthesis of Propargylamines via C–H Activation of Phenylacetylene

Autor:	Prashant B. Sarode, Hemant S. Chandak, Sandeep P. Bahekar
Rok vydání:	2016
Předmět:	chemistry.chemical_classification Solvent free 010405 organic chemistry Organic Chemistry Formaldehyde 010402 general chemistry Key features 01 natural sciences Aldehyde 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Phenylacetylene Organic chemistry
Zdroj:	Synlett. 27:2209-2212
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0035-1562114
Popis:	Zn(OTf)2-mediated expeditious and solvent-free synthesis of propargylamines via A3 coupling of aldehydes, amines, and phenylacetylene has been described. The described protocol proceeds effectively with variety of substituted benzaldehydes, enolizable aldehyde, and formaldehyde. Recyclability of the catalyst, low catalyst loading, and use of inexpensive catalyst are the key features of the present protocol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::752ed27a52fc8b34e6f5ebf413f4a8c3 https://doi.org/10.1055/s-0035-1562114 Zobrazit plný text záznamu