Bayesian-hierarchical pharmacokinetic/pharmacodynamic (PK/PD) model to characterize the exposure-QT effect relationship for decision making in early drug development

Autor:	Vincent F.S. Dubois, Roberta Bursi, Muriel Boulton
Rok vydání:	2016
Předmět:	Pharmacology Drug development business.industry Pharmacokinetic pharmacodynamic Bayesian probability Medicine Toxicology business PK/PD models
Zdroj:	Journal of Pharmacological and Toxicological Methods. 81:355
ISSN:	1056-8719
DOI:	10.1016/j.vascn.2016.02.066
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::74c7a6c304ad41f774526fe3bf23792f https://doi.org/10.1016/j.vascn.2016.02.066 Zobrazit plný text záznamu Full Text from ScienceDirect