Gallbladder: A rare primary site for small cell carcinoma
| Autor: | Krishnendu Mondal, Rupali Mandal, Dilip Chandra Barman |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pathology education.field_of_study biology business.industry Gallbladder Population Chromogranin A Neuroendocrine tumors medicine.disease Small-cell carcinoma medicine.anatomical_structure medicine biology.protein Immunohistochemistry Histopathology business education Mitosis |
| Zdroj: | Oncology, Gastroenterology and Hepatology Reports. 4:21 |
| ISSN: | 2348-3113 |
| DOI: | 10.4103/2348-3113.139629 |
| Popis: | Neuroendocrine tumors (NETs) are an extremely rare entity in gallbladder (GB), occurring in approximately 0.5% cases of NETs from all sites. In the present case report, a 42-year-old male presented with recurrent right upper quadrant pain for 2 months. Abdominal ultrasound revealed a small nodular swelling in the GB. On aspiration cytology that appeared as individual small tumor cells mostly in dispersed population and frequent nuclear molding within cell aggregates in a necrotic background. The patient was diagnosed as NET of GB. Histopathology revealed; uniform small rounded cells arranged in peritheliomatous pattern with intervening areas of massive necrosis. Nuclear molding, salt-pepper nuclear chromatin and frequent mitoses were also evident. Immunohistochemistry with chromogranin confirmed the diagnosis of small cell carcinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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