QUANTITATIVE ASSAY OF THE MELANOPHORE DISPERSING HORMONE DURING THE DEVELOPMENT OF THE CHICKEN PITUITARY1

Autor:	Hermann Rahn, Glenn A. Drager
Rok vydání:	1941
Předmět:	medicine.medical_specialty Hypophysectomy biology Hatching Ontogeny medicine.medical_treatment Embryo biology.organism_classification Chromatophore Anolis Rana Endocrinology Internal medicine medicine Hormone
Zdroj:	Endocrinology. 29:725-730
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-29-5-725
Popis:	TWO OBSERVATIONS SUGGESTED the rather early appearance of the melanophore dispersing hormone during ontogeny. It was first called to our attention by the results of hypophysectomy of the Spring peeper (Pseudacris triseriata) embryos. In these forms the melanophores were easily distinguished and revealed complete concentration of pigment at a time when the control animals were hatching from their jelly envelopes. Secondly preliminary experiments showed that head extracts of recently hatched Rana pipiens larvae yielded considerable amounts of melanophoredispersing hormone when injected into hypophysectomised Anolis lizards, while the control body extracts gave a negative response. Histological examination of control pituitaries revealed no cytoplasmic differentiation. These observations suggested, not only the presence of the melanophore'dispersing hormone in the undifferentiated gland, but also revealed its functional rOle during very early development.
Databáze:	OpenAIRE
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