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Drug Discovery for Neglected Diseases of the Developing World, P. Herrling Background The Drug Discovery Process Therapeutic Tools Drug Discovery Phases Phase I-Phase IIa Phase IIb-Phase III References Tuberculosis Biology and Drug Discovery, T. Dick Disease Manifestations and Treatment A Largely Unment Medical Need The Challenge of TB Drug Discovery An At las for TB Drug Discovery References Immunopathology of Tuberculosis Disease across Species, V. Dartois Overview of Species Specific Characteristics A Macroscopic View of TB-Infected Lungs across Species Summary and Lessons Learned References Anatomy and Histology of the Human Lung, F.J.W.-M. Leong and A. S.-Y. Leong Gross Structure Microscopic Structure References Pathology of Tuberculosis in the Human Lung, F.J.W.-M. Leong, S. Eum, L.E. Via, and C.E. Barry, 3rd Introduction Features Variations References Pulmonary Tuberculosis in Monkeys, J.L. Flynn and E. Klein Introduction Inoculum and Route of Infection Features Variations Strengths of This Animal Model Shortcomings References Pulmonary Tuberculosis in the Rabbit, G. Kaplan and L. Tsenova Introduction Inoculum and Route of Inoculation Features Strengths of This Animal Model Shortcomings References Pulmonary Tuberculosis in the Guinea Pig, R.J. Basaraba and I.M. Orme Introduction Inoculum and Route of Inoculation Features Strengths of This Animal Model Shortcomings References Pulmonary Tuberculosis in the Rat, A. Singhal, E.M. Aliouat, C. Creusy, G. Kaplan, and P. Bifani Introduction Inoculum and Route of Inoculation Features Variations Strengths of This Animal Model Shortcomings References Pulmonary Tuberculosis in the Mouse, S. Bharath and V. Balasubramanian Introduction Inoculum and Route of Inoculation Features Variations Strengths of This Animal Model Shortcoming References Glossary Index |
