ChemInform Abstract: Synthesis of Phosphodiesterase IVb Inhibitors. Part 2. Stereoselective Synthesis of Hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one and Tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one Derivatives

Autor:	V. A. Tartakovsky, A. V. Lesiv, Yu. A. Khomutova, S. L. Ioffe, Petr A. Zhmurov, A. Yu. Sukhorukov, Andrey A. Tabolin, M. S. Klenov
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Stereochemistry Chemistry Yield (chemistry) Phosphodiesterase Stereoselectivity General Medicine Nitrone
Zdroj:	ChemInform. 43
ISSN:	0931-7597
DOI:	10.1002/chin.201251030
Popis:	Starting from the known nitrone (I), the highly potent phosphodiesterase IVb inhibitors (VII) and (X) are stereoselectively synthesized in an overall yield of 22% and 18%, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7229d913c2629a8c1fae673ed47cbfb5 https://doi.org/10.1002/chin.201251030 Zobrazit plný text záznamu Plný text