A New Method for the Analysis of the Substitution Pattern of Hydroxyethyl(methyl)-Celluloses Along the Polysaccharide Chain
| Autor: | Petra Mischnick, Kristin Voiges, Julia Cuers, Inga Unterieser, Marian Rinken, Roland Adden |
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| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Electrospray Polymers and Plastics Organic Chemistry Substituent Cationic polymerization Oligosaccharide Condensed Matter Physics Reductive amination chemistry.chemical_compound Hydrolysis chemistry Reagent Polymer chemistry Materials Chemistry Organic chemistry Physical and Theoretical Chemistry Cellulose |
| Zdroj: | Macromolecular Chemistry and Physics. 214:1363-1374 |
| ISSN: | 1022-1352 |
| DOI: | 10.1002/macp.201300070 |
| Popis: | Hydroxyethylmethyl celluloses (MSHE 0.15–0.26, DSMe 1.49–1.82) and hydroxyethyl celluloses (MSHE 1.89–3.03) are analyzed with respect to their substituent distribution in the polymer chains. The cellulose ethers are peralkylated and partially hydrolyzed, and are analyzed by electrospray ionization-ion trap-mass spectrometry (ESI-IT-MS). The randomness of the partial hydrolysis is proven. Quantitative evaluation of their mass spectra becomes possible after labeling the oligosaccharides at the reducing end. Reductive amination with o-aminobenzoic acid gives better results than hydrazone formation with cationic Girard's T reagent. Syringe pump infusion gives more-accurate results compared with liquid chromatography (LC)-ESI-MS. Profiles of the substituent distribution in the oligosaccharide fractions of DP 2–DP 7 are compared with the theoretical random distribution of glucosyl units in the chain. |
| Databáze: | OpenAIRE |
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