Plasma Cholesteryl Ester and Phospholipid Transfer Proteins and their Regulation

Autor: John J. Albers, Toshio Nishide, Russell A. Faust, John H. Tollefson
Rok vydání: 1988
Předmět:
Zdroj: Advances in Experimental Medicine and Biology ISBN: 9781461280552
DOI: 10.1007/978-1-4613-0733-4_26
Popis: Recently, there has been intense interest in the role of plasma lipid transfer proteins in lipoprotein metabolism. It has been postulated that a cholesteryl ester transfer protein (CETP) plays a key role in “reverse cholesterol transport” by modulating the transfer of CE from high density lipoprotein (HDL) to chylomicrons, very low density lipoprotein (VLDL), lipoprotein remnants and low density lipoprotein (LDL).-’-These lipoprotein acceptors transport the CE to the liver. On the other hand, these CE acceptor lipoproteins are considered atherogenic particles and thus this CE transfer process could conceivably enhance atherosclerosis.
Databáze: OpenAIRE