Plasma Cholesteryl Ester and Phospholipid Transfer Proteins and their Regulation
Autor: | John J. Albers, Toshio Nishide, Russell A. Faust, John H. Tollefson |
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Rok vydání: | 1988 |
Předmět: |
Very low-density lipoprotein
biology Reverse cholesterol transport chemistry.chemical_compound High-density lipoprotein chemistry Biochemistry Low-density lipoprotein Cholesterylester transfer protein biology.protein Cholesteryl ester lipids (amino acids peptides and proteins) Lipoprotein Chylomicron |
Zdroj: | Advances in Experimental Medicine and Biology ISBN: 9781461280552 |
DOI: | 10.1007/978-1-4613-0733-4_26 |
Popis: | Recently, there has been intense interest in the role of plasma lipid transfer proteins in lipoprotein metabolism. It has been postulated that a cholesteryl ester transfer protein (CETP) plays a key role in “reverse cholesterol transport” by modulating the transfer of CE from high density lipoprotein (HDL) to chylomicrons, very low density lipoprotein (VLDL), lipoprotein remnants and low density lipoprotein (LDL).-’-These lipoprotein acceptors transport the CE to the liver. On the other hand, these CE acceptor lipoproteins are considered atherogenic particles and thus this CE transfer process could conceivably enhance atherosclerosis. |
Databáze: | OpenAIRE |
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