Autor: |
Rajneesh Kumar Singh, Selvakumar Balakrishnan |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
GI Surgery Annual ISBN: 9789811026775 |
DOI: |
10.1007/978-981-10-2678-2_1 |
Popis: |
Cancer is constituted by mutated cells that have escaped the normal checks and balances of regulated cell growth. It is initially localized to the organ of origin and thereafter spreads through the body, and ultimately becomes the cause of unnatural death of the patient. In the natural history of any cancer three distinct phases can be described: (i) limited to the organ of origin (localized phase); (ii) limited to the region of origin (regional phase); and (iii) spread to distant organs (metastatic phase) [1]. Regional phase/stage is usually described as spread limited to the regional lymph node basin. The philosophy of surgical lymphadenectomy, along with extirpation of the primary tumour, is meant to treat the regional stage of the disease. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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