The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations
| Autor: | Majid Sheykhzade, Grethe T Dalsgaard, Tue Johansen, Niels C. Berg Nyborg |
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| Rok vydání: | 2000 |
| Předmět: |
Pharmacology
medicine.medical_specialty endocrine system diseases business.industry Insulin medicine.medical_treatment Vasodilation medicine.disease Streptozotocin Muscle relaxation medicine.anatomical_structure Endocrinology Diabetes mellitus Internal medicine Circulatory system medicine business Pancreatic hormone Blood vessel medicine.drug |
| Zdroj: | British Journal of Pharmacology. 129:1212-1218 |
| ISSN: | 0007-1188 |
| DOI: | 10.1038/sj.bjp.0703159 |
| Popis: | This study investigates the effect of partially metabolic controlled long-term (34 weeks) streptozotocin (STZ)-induced diabetes on relaxation and contractile responses of isolated coronary arteries to seven different vasoactive agents. The average fasting and non-fasting blood glucose concentrations (mM) were significantly elevated in STZ-induced diabetic rats (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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