| Autor: |
Rufina Pérez, Liliana Calanni, Cristina Elena Canteros, Ricardo Negroni, J. L. Finquelievich, Susana Brasili, Norma Graciela Schmidt, C. Iovannitti, María Fernanda Zuiani |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Revista Iberoamericana de Micología. 30:193-199 |
| ISSN: |
1130-1406 |
| DOI: |
10.1016/j.riam.2012.12.007 |
| Popis: |
Background: In Argentina,there are no reports of autochthonous cases of histoplasmosis in the southern regions of the country. Aim: To report a histoplasmosis outbreak in Zapala town, Province of Neuquen, Patagonia Argentina. Methods: We evaluated the clinical and epidemiological characteristics of 5 patients involved in the outbreak. Environmental studies were conducted to determine the source of infection.The genetic pro?le of Histoplasma capsulatum strains isolated from the index case (IC) were compared with clinical isolates from Argentinean patients not related to the outbreak, using RAPD-PCR with primers 1281-1283. Results: The patients were residents of Zapala, and had not visited other geographical areas before. All patientshadanin?uenza-like syndrome, andX-ray revealed disseminated micronodular images throughout the lung parenchyma. The ICneeded speci?c antifungaltherapy;the remaining 4 patients had mild symptoms, and did not require therapy. All ofthem had a good clinical outcome. Strains of H. capsulatum isolated from blood culture and lung biopsy of the IC showed a genetic prole different fro mother strains |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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