| Autor: |
Hans Wildiers, A. Barbeaux, E. de Azambuja, L. van Walle, L. Van Eycken, N. Van Damme, François Duhoux, Didier Verhoeven, Peter Vuylsteke, Kevin Punie |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Annals of Oncology. 30:v75 |
| ISSN: |
0923-7534 |
| DOI: |
10.1093/annonc/mdz240.049 |
| Popis: |
Background A task force was created by the Belgian Society of Medical Oncology (BSMO) to monitor the quality of treatment of breast cancer in Belgium. In collaboration with the Belgian Cancer Registry an analysis of the data was performed in search of reliable quality indicators. Finding actionable differences can lead to better treatment of our patients. Methods Data of 48,872 patients diagnosed with invasive breast cancer between 2010 and 2014 were analysed. To enable risk stratification according to their surrogate subtype, pathology reports of year 2014 were manually checked (9,855 patients). We identified patients 75 Y receiving adjuvant radiotherapy after mastectomy and the different systemic treatments in each surrogate subtype. We also calculated the total length of endocrine treatment and the percentage of chemotherapy given in first line ER+ metastatic patients. Results In cStage I-III, post-mastectomy radiotherapy was administered in 70.7% of the patients 75 Y, with an important intercenter variability. 81.7% of the cStage I-III patients 70 Y. As first treatment for cStage IV HR+/HER2- patients, we identified endocrine therapy in 53.9% and chemotherapy in 17.3%. Conclusions Substantial treatment differences were observed among centers. Overtreatment is an important negative quality aspect of breast cancer management. A frequent use of postmastectomy radiotherapy was observed. The use of trastuzumab was inappropriate in pT1aN0 patients. Chemotherapy was used too often in first line hormone receptor positive metastatic patients. Legal entity responsible for the study Belgian Cancer Registry. Funding Has not received any funding. Disclosure All authors have declared no conflicts of interest. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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