Protein Production in Eukaryotic Cells
| Autor: | Diane Hatton, Richard Turner, Alan K. Hunter, Kripa Ram, Sanjeev Ahuja, Jean Bender |
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| Rok vydání: | 2016 |
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| Zdroj: | Topics in Medicinal Chemistry ISBN: 9783319418162 |
| DOI: | 10.1007/7355_2016_3 |
| Popis: | The scientific and engineering aspects of design, development, scale-up, and manufacture of monoclonal antibodies are summarized in this chapter by outlining the key elements in the development of the expression cell line, cell culture, cell harvest, and protein purification process and exploring the effect of process technologies on production economics. |
| Databáze: | OpenAIRE |
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