Modelling of Malignant Lymphoma in Rabbits, Using Oncogenic Viruses of Non-Human Primates

Autor: L.A. Yakovleva, L.V. Indzhiia, B.A. Lapin, M. T. Ivanov, Alexander Voevodin, V.V. Timanovskaya, D. S. Markaryan
Rok vydání: 1987
Předmět:
Zdroj: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540177548
DOI: 10.1007/978-3-642-72624-8_95
Popis: The discovery of lymphoid B-lymphotropic herpesvirus-producing cell lines from M. arctoides peripheral lymphocytes (MAL-1) producing their own lymphotropic virus HVMA was reported earlier [1]. Subsequently, two more M. arctoides virus-producing lymphoid cell lines (MAL-2, MAL-3) were discovered in our laboratory. The cells of some baboon lymphoid cultures, parallel with B-lymphotropic herpesvirus, produced C-type retrovirus antigenically similar to human T-lymphotropic virus (HTLV)-I. The cells of MAL-1, MAL-2 and MAL-3 cultures also produced B-lymphotropic herpesvirus, and small amounts of retrovirus particles were revealed (Fig. 1). Furthermore, it was reported that a number of Old World monkeys, including M. arctoides, can be the carriers of simian T-lymphotropic virus (STLV) related to HTLV-I [3].
Databáze: OpenAIRE