| Autor: |
Adel Saad, T.D. Chugh, Rita Dhar, P. M. Dhar, D. Panigrahi, Vincent O. Rotimi, S.C. Sanyal, Tina Lis Varghese, Adel Ghali |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
Anaerobe. 7:291-295 |
| ISSN: |
1075-9964 |
| DOI: |
10.1006/anae.2001.0404 |
| Popis: |
Clinical samples obtained from 200 patients with intra-abdominal infections were investigated for the presence of anaerobic bacteria. The majority of samples were from patients with appendicitis (108, 54%) followed by peritoneal abscess/peritonitis (37, 18.5%). A total of 153 anaerobes were isolated from 83 culture positive specimens with an isolation rate of 1.8 per sample. Ninety (59%) yielded Bacteroides fragilis group and B. fragilis stricto sensu accounted for half of them. Other isolates were 36 (23.5%) Prevotella species and 15 (9.8%) Peptostreptococcus micros . The susceptibility of the 153 isolates against eight antibiotics was determined by the E-test. All the isolates were susceptible to metronidazole, MIC 90 s varying between 1–2 μg/mL. The Prevotella spp., Peptostreptococcus spp., Fusobacterium spp. and Porphyromonas spp. were all susceptible to clindamycin (MIC 90 s=0.25–2 μg/mL respectively), imipenem (MIC 90 s=0.12–0.5μg/mL respectively) and meropenem (MIC 90 =0.25 μg/mL each). About 25% of the B. fragilis group were resistant to clindamycin with MIC more than 256 μg/mL. Piperacillin-tazobactam also exhibited excellent in vitro activity against all the isolates (MIC 90 =0.25 μg/mL). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect