ANTIBODY-MEDIATED PERINATAL CYTOPENIAS. 39

Autor:	D Suetti, A M Casadei Pistilli, D Regoli, R Pascone, E. Carapella De Luca
Rok vydání:	1997
Předmět:	biology business.industry Anemia Autoantibody Neutropenia medicine.disease Rh hemolytic disease Antigen hemic and lymphatic diseases Pediatrics Perinatology and Child Health Immunology biology.protein medicine Antibody business Rh blood group system Perinatal period
Zdroj:	Pediatric Research. 41:746-746
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-199705000-00058
Popis:	Anemia, thrombocytopenia and neutropenia in perinatal period may result from placentally transferred maternal IgG allo or autoantibodies against RBC, Plt and PMN antigens (Ags). Alloantibodies (alloAbs) against RBC Ags most commonly cause of severe fetoneonatal anemia are anti-D and other alloAbs of the Rh system (anti-c, anti-c plus anti-E) as well as anti-Kell. Although maternal anti-D immunoprophylaxis has dramatically reduced the prevalence of feto-neonatal Rh hemolytic disease, during the last decade in our Neonatal Unit 60 affected infants have been observed. More than 70% of them showed early plus late or late severe anemia which had often required prenatal and/or postnatal RBC transfusions (Ts).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6bca963a02c578dd6f5afbf027dbf757 https://doi.org/10.1203/00006450-199705000-00058 Zobrazit plný text záznamu