The chemistry of the opioid receptor binding sites

Autor:	K. Medzihradszky
Rok vydání:	2003
Předmět:	Pharmacology Chemistry medicine.drug_class Organic Chemistry Receptor specificity General Medicine Computational biology Biochemistry Structural Biology Opioid receptor Opioid Receptor Binding Drug Discovery medicine Molecular Medicine Binding site Opioid peptide Molecular Biology
Zdroj:	Journal of Peptide Science. 9:333-353
ISSN:	1099-1387 1075-2617
Popis:	Since the discovery of the opioid receptors and their endogenous ligands an immense research work has been devoted to the exploration of their specificity, the mechanism of ligand binding and ligand–receptor interactions. One of the main goals has been the location and characterization of the binding sites. The present review compiles the results achieved in this field in the last quarter of a century, and puts some questions concerning the success of these efforts. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
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