Rein et dysthyroïdies
Autor: | Victor Gueutin, Gilbert Deray, Romain Paule, Matthieu Ponsoye, Hassane Izzedine |
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Rok vydání: | 2013 |
Předmět: |
endocrine system
Kidney Creatinine medicine.medical_specialty endocrine system diseases urogenital system business.industry Thyroid Renal function Nephron urologic and male genital diseases medicine.disease Gastroenterology chemistry.chemical_compound medicine.anatomical_structure chemistry Nephrology Internal medicine medicine Thyroid function business Nephrotic syndrome hormones hormone substitutes and hormone antagonists Homeostasis |
Zdroj: | Néphrologie & Thérapeutique. 9:13-20 |
ISSN: | 1769-7255 |
DOI: | 10.1016/j.nephro.2012.06.005 |
Popis: | Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron, and sodium and water homeostasis. Effects of hypothyroidism and hyperthyroidism on kidney function are the result of direct renal effects, as well as systemic hemodynamic, metabolic, and cardiovascular effects. Most of the renal manifestations of thyroid disorders, which are clinically most significant with hypothyroidism, are reversible with treatment. Patients with hypothyroidism can have clinically important reductions in GFR, so screening for hypothyroidism should be considered in patients with unexplained elevations in serum creatinine. Patients with thyroid disorders are also at risk for immune-mediated glomerular diseases. Finally, patients with nephrotic syndrome, as well as acute and chronic kidney injury, have alterations in thyroid gland physiology that can impact thyroid function and the testing of thyroid function status. Dialysis patients have frequently hypothyroidism whose biological diagnosis must be careful. |
Databáze: | OpenAIRE |
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