Primary gastrointestinal T-cell lymphomas: concepts and diagnostic insights
| Autor: | Jessica Alvarez Lesmes, Julio Poveda |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Gastrointestinal tract Pathology medicine.medical_specialty Histology Heterogeneous group Intestinal T-cell lymphoma business.industry T cell Not Otherwise Specified medicine.disease Pathology and Forensic Medicine Lymphoma 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure immune system diseases hemic and lymphatic diseases 030220 oncology & carcinogenesis medicine T-cell lymphoma business Who classification |
| Zdroj: | Diagnostic Histopathology. 27:57-61 |
| ISSN: | 1756-2317 |
| DOI: | 10.1016/j.mpdhp.2020.11.001 |
| Popis: | The gastrointestinal tract represents the most common site of extranodal non-Hodgkin lymphoma. Malignant lymphomas represent up to 4% of all malignant neoplasms of the GI tract. Overall, lymphomas of B-cell lineage predominate. T-cell lymphomas are uncommon and account for 6% of all GI tract lymphomas. Intestinal T-cell lymphomas comprise a heterogeneous group of lymphoproliferative neoplasms with distinct morphologic, immunophenotypic, and genetic features. Based on the recently revised 2017 WHO classification, intestinal T-cell lymphomas are categorized into four distinct entities: Enteropathy-associated T-cell lymphoma (EATL), monomorphic epitheliotropic intestinal T-cell lymphoma (METL), intestinal T-cell lymphoma, not otherwise specified (ITCL, NOS) and indolent T-cell lymphoproliferative disorder of the gastrointestinal tract. Herein, we aim to create awareness of these uncommon neoplasms with emphasis on key diagnostic points. |
| Databáze: | OpenAIRE |
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