Sleep, Fatigue, Depression, and Pain in Mexican Women With Systemic Lupus Erythematosus: An Exploratory Study

Autor: Montserrat Resendiz, Natasha Alcocer, Rosa M. Campos, Guillermo García-Ramos, Matilde Valencia-Flores, Marcos Modiano, Ángel Camarena, Rafael J. Salín-Pascual, Victoria Santiago, Violeta A. Castaño, Julio Granados, Ramcés Falfán-Valencia
Rok vydání: 2010
Předmět:
Zdroj: Hispanic Health Care International. 8:217-226
ISSN: 1540-4153
Popis: ] age = 39.3 [11.1] underwent nocturnal polysomnography (PSG) and daytime testing (Multiple Sleep Latency Test, [MSLT]) and were compared to healthy female age-matched controls. We employed validated instru-ments to assess disease activity, fatigue, and depressive symptoms. Results: SLE patients had lower sleep efficiency, greater number of awakenings, and greater time awake after sleep onset than controls. The majority (over 70%) of SLE patients were sleepy (mean MSLT 6.7 ± 3.9 minutes). Clinically sleep com-plaints scores were higher than the control group and they correlated with PSG total sleep time, time of oxygen desaturation, Apnea and Hypopnea Index (AHI), and Periodic Limb Movement Index (PLMI). Conclusion: Poor nocturnal sleep and daytime sleepiness are common in SLE patients. Sleepiness (MSLT) in SLE may be associated with total sleep time of oxygen desaturation and sleep fragmentation. Our study also confirmed previous findings that sleep apnea and periodic limb movements while you sleep (PLMS) are common sleep disorders in patients with SLE.
Databáze: OpenAIRE