Strain measurement for 2D echo with ultrasound enhancing agents can be performed with software available for non-enhanced recordings

Autor: M Church, B Foster, J Choy, E Pituskin, DI Paterson, H Becher
Rok vydání: 2022
Předmět:
Zdroj: European Heart Journal - Cardiovascular Imaging. 23
ISSN: 2047-2412
2047-2404
DOI: 10.1093/ehjci/jeab289.048
Popis: Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): ABACUS Cardiovascular Research Centre, Mazankowski Alberta Heart Institute Background Global longitudinal strain (GLS) measurement are less reliable when 2D image quality is reduced. While ultrasound enhancing agents (UEA; also known as "echo contrast") have been shown to enhance the reliability of EF measurements, there has been sparse evidence on performing GLS measurements after UEA injection. The aim of this study was to assess the feasibility of GLS analysis using the same software validated for non-enhanced 2D recordings. Methods GLS measurements were performed before and after injection of an approved UEA in 131 patients with acceptable image quality for GLS measurements. These patients were referred prior to chemotherapy initiation or were being monitored for potential cardiotoxic effects. As all these patients undergo echocardiography with UEA in order to achieve the best reproducibility of EF measurements, comparison of GLS measurements with and without UEA was possible. A commercially available ultrasound system was used and the same analysis software was applied. On end-diastolic and end-systolic frames, the inner border of the region of interest was manually adjusted to align with interface between the compact and trabeculated myocardium on non-enhanced images and the LV blood pool on the recordings with UEA. Results GLS measurements on recordings with UEA were performed in 131 patients. A strong positive correlation (r 0.67, p 2% between methods were related to foreshortening or suboptimal delineation of segments on non-contrast recordings. Conclusion On a commercially available echocardiography scanner, software developed for GLS measurements on non-enhanced 2D recordings can be also applied to recordings that use UEA. Comparable results are obtained, provided the LV cavity is well delineated and not foreshortened. Abstract Figure 1
Databáze: OpenAIRE