Clinical and therapeutic patterns of lower extremity amputation (LEA) in a tertiary hospital in Togo: a retrospective study

Autor: Têtê Edem KOUEVI-KOKO, Komla Sena Amouzou, Ananivi Sogan, Sodjehoun Apeti, Yao Eme Lumière Dakey, Anani Abalo
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1359470/v1
Popis: Background We analysed the clinical and therapeutic profile of the patients who underwent a surgical lower extremity amputation (LEA) in Togo. Methods Retrospective study based on clinical files of the adult patients who underwent a LEA at a single centre (Sylvanus Olympio Teaching Hospital, SOTH) from 1st January 2010 to 31st December 2020. We analysed files with 95% of the studied parameters and excluded those with less than 5%. Data were analysed by CDC Epi Info Version 7 and Microsoft Office Excel 2013 software. Results We included 245 cases. The mean age was 59.62 years (15.22SD) (range 15 to 90 years), the sex ratio, 1.99. The medical history of diabetes mellitus was found in 143/222 (64.41%). Gangrene was diagnosed in 212/245 (86.53%) patients; crush syndrome in 23/245 (9.39%); bone tumour in 5/245 (2.04%); osteomyelitis in 2/245 (0.82%); chronic ulcer in 2/245 (0.82%); necrosis fasciitis in 1/245 (0.40%). A Doppler-ultrasound of the lower limbs was performed in 91/245 (37.14%) cases. The anatomical site of LEA found in 241/245 (98.37%) files was leg in 133/241 (55.19%), knee in 14/241 (5.81%), thigh in 83/241 (34.44%), and foot in 11/241 (4.56%) patients. The mean delay from the indication of amputation to surgery retrieved in 239/245 (97.55%) files was 6.75 (1–78) days (11.59 SD). The immediate postoperative complications have been reported in 242/245 (98.78%) files, and no complication in 234/242 (96.69%). There were early complications in 56/238 (23.53%) patients. The mortality rate after LEA was 17/238 (7.14%). The mean duration of hospitalization marked in 241/245 (98.37%) files was 36.30 (1-278) days (36.20SD). Conclusion Most patients admitted to SOTH (Lomé, Togo) who underwent LEA had diabetes mellitus at the late presentation, which led to challenging complications. This result entails essential information campaigns to prevent diabetes mellitus and cardiovascular diseases.
Databáze: OpenAIRE