The preterm prediction study: Risk factors for indicated preterm births

Autor: S. F. Bottoms, D. McNellis, James M. Roberts, G. R. Thurnau, M. Miodovnik, A. H. Moawad, S. N. Caritis, Brian M. Mercer, A. Das, Paul J. Meis, J. D. Iams, R. L. Goldenberg, M. K. Menard
Rok vydání: 1998
Předmět:
Zdroj: American Journal of Obstetrics and Gynecology. 178:562-567
ISSN: 0002-9378
DOI: 10.1016/s0002-9378(98)70439-9
Popis: OBJECTIVE: Preterm births occur for many different reasons. Most efforts to identify risk factors for preterm births either ignore cause and consider preterm births as a single entity or examine risk factors for spontaneous preterm births. We performed this study to examine risk factors for indicated preterm births, which constitute more than one quarter of all preterm births. STUDY DESIGN: The study included 2929 women evaluated at 24 weeks' gestation at 10 centers. Information was gathered about demographic factors, socioeconomic status, home and work environments, drug and alcohol use, and medical history. In addition vaginal samples were evaluated for fetal fibronectin and bacterial vaginosis and cervical length was measured by transvaginal ultrasonography. Associations with indicated preterm birth were evaluated by univariate tests and by multivariable analysis with logistic regression. RESULTS: Of the women studied at 24 weeks' gestation 15.3% were delivered of their infants at 30 years (odds ratio 2.42), black ethnicity (odds ratio 1.56), and working during pregnancy (odds ratio 1.49). Alcohol use in pregnancy was actually associated with a lower risk of indicated preterm birth (odds ratio 0.35). CONCLUSION: The risk factors found in this analysis tend to be different from those associated with spontaneous preterm birth. (Am J Obstet Gynecol 1998;178:562-7)
Databáze: OpenAIRE
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