Exact Poly-KTest

Autor: Karl K. Lin, Ram C. Tiwari, Matthew Jackson, Mohammad A. Rahman
Rok vydání: 2014
Předmět:
Zdroj: Communications in Statistics - Simulation and Computation. 45:2257-2266
ISSN: 1532-4141
0361-0918
DOI: 10.1080/03610918.2014.901351
Popis: For animal carcinogenicity study with multiple dose groups, positive trend test and pairwise comparisons of treated groups with control are generally performed using the Cochran-Armitage, Peto test, or Poly-K test. These tests are asymptotically normal. The exact version of Cochran-Armitage and Peto tests are available based on the permutation test assuming fixed column and row totals. For Poly-K test column totals depend on the mortality pattern of the animals and can not be kept fixed over the permutations of the animals. In this work a modification of the permutation test is suggested that can be applied on exact Poly-K test.
Databáze: OpenAIRE