Focal segmental glomerulosclerosis after renal transplantation
| Autor: | Emiko Fujita, Seiichiro Higo, Akira Shimizu, Akiko Mii, Tomohiro Kaneko |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Transplantation
Pathology medicine.medical_specialty medicine.diagnostic_test biology urogenital system business.industry Transplant glomerulopathy Gene mutation urologic and male genital diseases medicine.disease female genital diseases and pregnancy complications Surgery Focal segmental glomerulosclerosis medicine Podocin biology.protein Renal biopsy business Kidney transplantation Kidney disease |
| Zdroj: | Clinical Transplantation. 25:6-14 |
| ISSN: | 0902-0063 |
| DOI: | 10.1111/j.1399-0012.2011.01452.x |
| Popis: | Focal segmental glomerulosclerosis (FSGS) is a clinicopathologic syndrome of proteinuria, usually of nephrotic range, associated with focal and segmental sclerotic glomerular lesions. Therefore, FSGS is diagnosed by clinical features and histopathological examination of renal biopsy. The natural history of the condition varies, and although it may respond to treatment, FSGS is an important disease in the etiology of end-stage renal disease (ESRD). Furthermore, after kidney transplantation, approximately 30% of patients with FSGS develop recurrent FSGS. The risk factors for recurrence of FSGS include childhood onset and age |
| Databáze: | OpenAIRE |
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