Direct and Regioselective Palladium(II)-Catalyzed B(4)–H Monoacyloxylation and B(4,5)–H Diacetoxylation of o-Carborane Acids with Phenyliodonium Dicarboxylates

Autor:	Hyeongcheol Ham, Heejin Yang, Hanjoong Kim, Chanyoung Maeng, Kyungsup Lee, Tae Hyeon Kim, Sang Hoon Han, Gi Hoon Ko, Gi Uk Han, Phil Ho Lee, Seohyun Shin, Hee Chan Noh
Rok vydání:	2021
Předmět:	Chemistry Organic Chemistry Carborane Regioselectivity chemistry.chemical_element Selectivity Medicinal chemistry Catalysis Palladium
Zdroj:	The Journal of Organic Chemistry. 86:15153-15163
ISSN:	1520-6904 0022-3263
Popis:	A direct B(4)-H monoacyloxylation via a Pd-catalyzed regioselective B(4)-H activation of o-carborane acids with phenyliodonium dicarboxylates was developed, and a series of B(4)-H monoacyloxylated o-carboranes decorated with active groups were synthesized with moderate to good yields as well as excellent selectivity. In addition, a direct B(4,5)-H diacetoxylation from o-carborane acids with phenyliodonium diacetate was demonstrated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::67b70046b5c7794546120bd3e54f6b26 https://doi.org/10.1021/acs.joc.1c01804 Zobrazit plný text záznamu