Preparation of chitosan/PLA blend micro/nanofibers by electrospinning

Autor: Weiquan Gao, Hongwei Liang, Jia Xu, Jinhui Zhang, Junfeng Li, Hongyan Wang
Rok vydání: 2009
Předmět:
Zdroj: Materials Letters. 63:658-660
ISSN: 0167-577X
DOI: 10.1016/j.matlet.2008.12.014
Popis: The chitosan/PLA blend micro/nanofibers have been prepared for the first time by electrospinning. Trifluoroacetic acid (TFA) was found to be the co-solvent for electrospinning. The chitosan/PLA blend solutions in various ratios were studied for electrospinning into micro/nanofibers. The morphology of the fibers was shown by scanning electron microscope (SEM). It was found that the average diameter of the chitosan/PLA blend fibers became larger, and the morphology of the fibers became finer with the content of PLA increasing. To show the molecular interactions, chitosan/PLA fibers were characterized by Fourier transform infrared spectroscopy (FTIR). The spun micro/nanofibers are expected to be used in the native extracellular matrix for tissue engineering.
Databáze: OpenAIRE