Homogenous Iron-Catalysed Deuteration of Electron-Rich Arenes and Heteroarenes

Autor: Matthias Beller, Kathrin Junge, Florian Bourriquen
Rok vydání: 2022
Předmět:
Zdroj: Synlett. 34:332-336
ISSN: 1437-2096
0936-5214
Popis: Deuterated organic molecules are of interest for many applications ranging from mechanistic investigations in basic organic and physical chemistry to the development of new pharmaceuticals. Thus, methodologies for isotope-labelling reactions continue to be important. Here, a convenient methodology for hydrogen/deuterium exchange reactions in electron-rich arenes is reported using simple iron salts and deuterium oxide as isotope source.
Databáze: OpenAIRE