Role of cervicovaginal β-hCG in prediction of preterm delivery: a prospective observational study
| Autor: | Ritika Gupta, Harpreet Kaur, Priyanka Mukherjee, Sahil Singhal |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 9:3677 |
| ISSN: | 2320-1789 2320-1770 |
| Popis: | Background: The World Health Organization (WHO) factsheet revealed that 15 million babies are born too early every year and almost 1 million children die each year due to complications of preterm birth. The objective of this study was to determine whether cervicovaginal β-hCG level can be used as predictor of preterm delivery in asymptomatic high-risk pregnant women at 24-34 weeks gestation age.Methods: This was prospective observational study. Total 134 asymptomatic pregnant women were taken for study who had at least one risk factor for preterm delivery at 24-34 weeks gestation age. Cervicovaginal secretion was collected and β-hCG level was measured by chemiluminescent immunoassay.Results: Out of 134 cases, 42.5% had preterm delivery and 57.5% had term delivery. Mean cervicovaginal β-hCG level (mIU/ml) in preterm delivery group was 39.38±19.66 and term delivery group was 21.86±11.18. Cervicovaginal β-hCG level was significantly higher in preterm group compare to term group demonstrating significant association of raised β-hCG with preterm group (p value |
| Databáze: | OpenAIRE |
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