A chronobiological study of cell multiplication in esophageal epithelium of mice given lomefloxacin at different times of the day

Autor:	O. A. Irikov, Yu. A. Romanov, S. S. Filippovich
Rok vydání:	1994
Předmět:	Chronobiology medicine.medical_specialty Mitotic index Cell division Period (gene) Cell General Medicine Biology General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Rhythm Endocrinology Internal medicine medicine Lomefloxacin Circadian rhythm medicine.drug
Zdroj:	Bulletin of Experimental Biology and Medicine. 117:526-529
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02444308
Popis:	The diurnal rhythmic pattern of cell division is preserved after both afternoon and night injection of lomefloxacin, but a rightward phasic shift of the diurnal rhythm is observed, the amplitude of rhythmic fluctuations being unchanged. In both cases the mesor of the mitotic index virtually does not, differ from that of the control, and the pool of dividing cells over 24 hours and throughout the follow-up period is even larger than the control values, which attests to a high adaptive potential of the proliferative system of esophageal epithelium.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::65c1cff6cdd8aa9f268d973452324a73 https://doi.org/10.1007/bf02444308 Zobrazit plný text záznamu Full text from SpringerLink