V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells

Autor: Annie Ehler, Xiaopeng Li, Raul Villacreses, David K. Meyerholz, Steven E Mather, Adam Zabner, Joseph Zabner, David A. Stoltz, Christian M Brommel, Ian M. Thornell, Lin Lu, Julio Noriega
Rok vydání: 2021
Předmět:
Zdroj: American Journal of Respiratory Cell and Molecular Biology. 65:146-156
ISSN: 1535-4989
1044-1549
DOI: 10.1165/rcmb.2020-0349oc
Popis: In a newborn pig cystic fibrosis (CF) model, the ability of gland-containing airways to fight infection was affected by at least two major host-defense defects: impaired mucociliary transport and a...
Databáze: OpenAIRE