Antibiotic Resistance in the Intensive Care Unit

Autor: F. Marco, Jordi Vila
Rok vydání: 2007
Předmět:
Zdroj: Infectious Diseases in Critical Care ISBN: 9783540344056
Popis: Nosocomial infections, especially those caused by antibacterial agent-resistant pathogens, represent an important source of morbidity and mortality for the patients in an ICU. Important antibacterial agent-resistant nosocomial pathogens include both Gram-negative (ESBL-producing Enterobacteriaceae and non-fermenting bacilli, such as Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia) and Gram-positive (methicillin-resistant Staphylococcus aureus [MRSA] and vancomycin-resistant Enterococcus spp. [VRE]) bacteria. Overall, the prevalence of resistance is often highest in units where the most vulnerable patients are located and where antibacterial use is consequently the heaviest. For instance, ICU patients have shown twofold higher rates of MRSA, ceftazidime resistance among Enterobacter cloacae and P. aeruginosa, and vancomycin resistance among enterocci than in patients in general wards [1].
Databáze: OpenAIRE