Histologic Processing of Thick Tissue Specimens from Cytology Slides

Autor:	Frank Smedts, Dick H. Verbeek, Carolien W. Wijnen-Dubbers, Marcel Mravunac
Rok vydání:	1996
Předmět:	Novel technique Diagnostic information Histocytological Preparation Techniques Pathology medicine.medical_specialty Histology medicine.diagnostic_test business.industry General Medicine Pathology and Forensic Medicine Cytopathology Cytology Biopsy medicine business
Zdroj:	Acta Cytologica. 40:1198-1204
ISSN:	1938-2650 0001-5547
DOI:	10.1159/000333980
Popis:	OBJECTIVE: To describe a novel method by which small tissue fragments found in routine cytology specimens can be processed for histologic slides without destroying or damaging the cytologic specimen. STUDY DESIGN: To develop a method by which small tissue fragments (microbiopsies) are removed from cytologic slides and processed through paraffin or plastic, after which histologic slides can be prepared. RESULTS: In all cases described, the histologic sections from the microbiopsies were of excellent quality. Microscopic examination gave additional important information. Furthermore, immunochemistry could be performed on paraffin-processed microbiopsies. CONCLUSION: This method can be of great value in cytologic specimens in which microbiopsies are present, not only in those cases in which cytologic information is insufficient for diagnosis, but also in cases with conclusive diagnostic information. Routinely applied, this method could make biopsies unnecessary in some cases.
Databáze:	OpenAIRE
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