High-sensitivity troponin T in preterm infants with a hemodynamically significant patent ductus arteriosus
| Autor: | Hana Ramadan Omar, Neveen Tawfik Abed, Asmaa Adel El-Falah, Mostafa Ebrahim Elsayes |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :8220-8230 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns6.11990 |
| Popis: | Background: The incidence of patent ductus arteriosus (PDA) is inversely related to gestational age. Cardiac troponin T (cTnT) is a specific marker for myocardial ischemic injury. The aim of this work was to investigate if a hemodynamically significant patent ductus arteriosus leads to elevated high- sensitivity troponin T (hsTnT) levels in serum. Methods: This prospective observational research included 60 preterm infants 1.5 mm and LA: Ao >1.2 and group B: preterm infants without hs.PDA. All cases were subjected to clinical examination, echocardiogram and hsTnT assay. Results: Serum hsTnT levels was significantly elevated in patients with hs PDA compared to patients without hs PDA. High sensitive T-troponin can significantly detect hsPDA with AUC of 0.986, P value 100 pg/ml, it’s a significant detector with sensitivity of 93.33%, specificity of 90%, PPV of 90.3, NPV of 93.1 and diagnostic accuracy of 91.5%. PDA had a significant positive correlation with hsTnT (r=0.803, P |
| Databáze: | OpenAIRE |
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