PWE-302 Colorectal cancer lymph node retrieval number is associated with biological and institutional factors: a tertiary centre audit
| Autor: | R. J. Davies, Nicola S Fearnhead, JM Wheeler, SJ Buczacki, CJ Deutsch, N. R. Hall, R. Miller, MP Powar |
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| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Gut. 64:A344.1-A344 |
| ISSN: | 1468-3288 0017-5749 |
| Popis: | Introduction Increased numbers of lymph nodes (LN) retrieved within a colorectal cancer resection is positively associated with survival and as such, identification of ≥12 LN is considered to be a surgical quality indicator. Here we audited LN retrieval data to establish both quality compliance and identify factors affecting identification rates. Method All colorectal cancer resections from April 2012–October 2014 at our institution were identified from the hospital’s cancer registry. The primary outcome variable was the number of nodes identified within the resection. Results 398 cases were included with a median LN retrieval number of 16. Greater numbers of nodes were identified in laparoscopic versus open surgery (p Conclusion Local compliance in the identification of ≥12 nodes was achieved. Audit analysis of LN retrieval data provides insight into the biology of colorectal cancer as well as identifying institutional specific predictors of LN yield. Disclosure of interest None Declared. References Berger AC, Sigurdson ER, LeVoyer T, Hanlon A, Mayer RJ, Macdonald JS, et al . Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005;23(34):8706–12 Buczacki SJA and Davies RJ. Colon resection - is standard technique adequate? Surg Oncol Clin N Am . 2014 Jan;23(1):25–34 Chang GJ, Rodriguez-Bigas MA, Skibber JM, Moyer VA. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Cancer Inst. 2007;99(6):433–41 Gilchrist RK, David VC. Lymphatic Spread of Carcinoma of the Rectum. Ann Surg. 1938;108(4):621–42 Le Voyer TE, Sigurdson ER, Hanlon AL, Mayer RJ, Macdonald JS, Catalano PJ, et al . Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003;21(15):2912–9 Lykke J, Roikjaer O, Jess P. The relation between lymph node status and survival in Stage I-III colon cancer: results from a prospective nationwide cohort study. Colorectal Dis. 2013;15(5):559–65 |
| Databáze: | OpenAIRE |
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