Induction of Autoantibodies by Human Immunodeficiency Virus Infection and Their Significance

Autor: Evelyn V. Hess, Alan M. Solinger
Rok vydání: 1991
Předmět:
Zdroj: Rheumatic Disease Clinics of North America. 17:157-176
ISSN: 0889-857X
DOI: 10.1016/s0889-857x(21)00095-8
Popis: SUMMARY Although many of the changes in HIV and AIDS appear to be global, on closer investigation the defects are specific and can be explained by recognized mechanisms. Despite a demonstrated concurrent polyclonal B-cell activation, studies fail to show any evidence to date of significant dysregulation of the immune system leading to serologic or clinical autoimmunity.
Databáze: OpenAIRE