Le carcinome à cellules de Merkel revisité : un nouvel exemple de tumeur humaine viro-induite

Autor:	X. Sastre-Garau
Rok vydání:	2011
Předmět:	integumentary system Merkel cell carcinoma viruses virus diseases food and beverages General Medicine Disease Biology medicine.disease_cause medicine.disease Virus medicine Carcinoma Cancer research Neuroendocrine carcinoma Carcinogenesis
Zdroj:	Pathologie Biologie. 59:127-130
ISSN:	0369-8114
DOI:	10.1016/j.patbio.2010.07.007
Popis:	Merkel cell carcinoma (MCC) is a neuroendocrine carcinoma of the skin of poor outcome. A new type of virus, isolated in 2008, was found to be strongly associated with CCM. This virus, belonging to the family of polyomavirus, was called MCPyV for Merkel Carcinoma Polyomavirus. Recent data favour a causative role of MCPyV in oncogenesis. MCC represents thus a new model for the understanding of the mechanisms of oncogenesis. The distinct molecular viral signature in every case of MCC represents an original tool for the follow-up of the disease. New therapeutic perspectives are to be drawn using this model.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::63425772c23a6d7dcee61406627f7846 https://doi.org/10.1016/j.patbio.2010.07.007 Zobrazit plný text záznamu Full Text from ScienceDirect