| Autor: |
AE Udoh, Mahmoud B Alhassan, E. C. Akwiwu, Faith A. Effa, MH Etukudo, Iya Eze Bassey, Paulinus Jimmy Unung |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Health Science Research. :27-34 |
| ISSN: |
2456-2688 |
| DOI: |
10.7324/jhsr.2021.624 |
| Popis: |
Context: the role of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) on renal function of diabetics is unclear. Objective: This study investigated the relationship between VEGF, PEDF and urea, creatinine and estimated glomerular filtration rate (eGFR) in type 2 diabetics. Materials and Methods: 100 type 2 diabetics and 50 controls were recruited into this case-control study. Analytes were determined by standard methods. Statistical significance was set at p0.05) in both groups. VEGF and PEDF were comparable (p>0.05) in the diabetics with eGFR60 ml/min. Renal function parameters did not correlate with either VEGF or PEDF. Conclusion: plasma VEGF and PEDF are higher in diabetics but there seem to be no association between renal function determinants and either VEGF and PEDF. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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