Assessment of Cognitive Function Before and After Surgery for Posterior Cranial Fossa Lesions

Autor:	Masahito Kobayashi, Maaya Orii, Shinya Ishimura, Takayuki Ohira, Takeshi Kawase, Tadashige Kano, Atsushi Fukunaga
Rok vydání:	2009
Předmět:	medicine.medical_specialty Mini–Mental State Examination medicine.diagnostic_test business.industry Neuropsychology Cognition Middle cranial fossa Normal limit Surgery medicine.anatomical_structure Posterior cranial fossa medicine Operative time Neurology (clinical) Neurosurgery business
Zdroj:	Skull Base. 19
ISSN:	1532-0065 1531-5010
DOI:	10.1055/s-2009-1242320
Popis:	Background: Cognitive function after neurosurgery for posterior fossa lesions has not been well studied despite its potential importance in determining surgical indications and approaches. The aim of this study is to evaluate changes in cognitive functions after posterior fossa surgery and to detect any differences between the middle cranial fossa (MF) and lateral suboccipital (SO) approaches. Method: Fifty patients with posterior fossa lesions such as tumors and vascular diseases were included in this study. Twenty-five patients underwent surgery via the MF and 25 via the SO approach. Computerized test battery (CogState) and conventional neuropsychological tests (serial seven-word learning test and Mini Mental State Examination) were examined before and at 1 and 3 months after surgery. Findings: After the surgery, all the scores of the neuropsychological tests remained within normal limits. In the MF group, however, the scores of one patient's results from the computerized test battery and serial seven-word learning tests decreased significantly 1 month after surgery and recovered within 3 months, indicating temporary deterioration of short-term memory. The computerized tests detected significantly larger numbers of patients with worsened results than the conventional tests. The MF approach and operative time showed correlations with the postoperative neuropsychological declines. Conclusions: The computerized tests could be performed easily and were beneficial for detecting subtle changes of the cognitive function after surgery. After posterior fossa neurosurgery, cognitive function, especially short-term memory, may decline temporarily with the MF approach and long operative time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::61f6a670013eb95d357c0bfdd76588f7 https://doi.org/10.1055/s-2009-1242320 Zobrazit plný text záznamu