Primary lymphoma of the trigeminal nerve presenting as infra‐orbital paraesthesia: A case report and literature review

Autor: Shreya Tocaciu, Yi Zhao, Sevastjan Kranz, David Wiesenfeld, Michael Dickinson, Christine Goh
Rok vydání: 2020
Předmět:
Zdroj: Oral Surgery. 14:216-220
ISSN: 1752-248X
1752-2471
DOI: 10.1111/ors.12584
Popis: Background: Primary lymphoma of the trigeminal nerve is very rare, with only 10 cases reported in the literature. It may present as unexplained paraesthesia of the trigeminal nerve, usually affecting all three divisions of the nerve. To date, a collation of the known cases of primary trigeminal nerve lymphoma is lacking. This study presents a literature review on trigeminal nerve lymphoma, and presents a case to illustrate diagnosis and management. Methods: The case report of primary trigeminal lymphoma is presented, with long-term follow-up. A review of the known cases of primary trigeminal lymphoma is conducted, demonstrating the current understanding on diagnosis and management of these rare lesions. Results: A 67-year-old man presented with a 4-month history of infra-orbital paraesthesia. Imaging showed an expanded infra-orbital canal, with changes extending to the vidian canal. The lesion was biopsied via an endoscopic trans-antral approach, and a diffuse large B-cell lymphoma was confirmed. He was managed with multi-agent chemotherapy with a good clinical response. Conclusions: Although rare, primary trigeminal lymphoma is an important additional differential diagnosis to consider when assessing a new finding of unexplained trigeminal nerve paraesthesia. Central nervous system imaging should be included in the work up of unexplained trigeminal paraesthesia.
Databáze: OpenAIRE
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