ChemInform Abstract: A Versatile Synthesis of 'Tafuramycin A': A Potent Anticancer and Parasite Attenuating Agent
Autor: | Peter Conrad Healy, Faith Josephine Rose, Mark von Itzstein, Ibrahim M. El-Deeb |
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Rok vydání: | 2014 |
Předmět: | |
Zdroj: | ChemInform. 45 |
ISSN: | 0931-7597 |
Popis: | The improved synthesis of tafuramycin A (I) includes a regioselective bromination step, a controlled aryl radical alkene cyclization to prevent dechlorination, and a new protection/deprotection method to avoid double bond reduction of the furan ring during deprotection of the benzyl group. |
Databáze: | OpenAIRE |
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