Puumala-Virus Infektion (Nephropathia epidemica) als Differenzialdiagnose der akut aufgetretenen Niereninsuffizienz
| Autor: | Stöffler-Meilicke M, Pohly M, Scherübl H, Schwarz A, Stockmann M |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Creatinine Proteinuria biology medicine.diagnostic_test business.industry Interstitial nephritis General Medicine biology.organism_classification medicine.disease Gastroenterology chemistry.chemical_compound chemistry Internal medicine Nephropathia epidemica Vomiting Medicine Puumala virus Renal biopsy medicine.symptom business |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 127:557-560 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-2002-22047 |
| Popis: | UNLABELLED Puumala virus infection (nephropathia epidemica) as different diagnosis of acute renal failure. HISTORY A 34-year old patient presented in reduced status with a sudden onset of fever, headache, backpain, abdominal pain, mild diarrhea, nausea with vomiting, and blurred vision. Within a few days an acute renal failure developed. INVESTIGATIONS On admittance there was thrombocytopenia of 27/nl, CRP of 109 mg/l and proteinuria of 5 g/l, moderate glucosuria and erythrocyturia of 250/microliter. Renal biopsy showed acute hemorrhagic interstitial nephritis. DIAGNOSIS, THERAPY AND FOLLOW UP: Diagnosis of nephropathia epidemica was proven by puumala-virus IgM- and later IgG-antibodies. Hantaan-antibodies were negative. Maximum serum creatinine of 640 micromol/l and urea of 30.5 mmol/l developed on the 5(th) day after admission. Without specific therapy the patient recovered fast and there were no persisting abnormalities during a 2-year follow up. CONCLUSION In young patients with acute renal failure of unknown origin with the above symptoms hantavirus-infection with the subtypes puumala and dobrava should be considered in Central Europe. |
| Databáze: | OpenAIRE |
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