Liberation of Lithium from Sustained Release Preparations

Autor: Müller-Oerlinghausen B, Heim W, Oelschläger H, Kreuter J
Rok vydání: 1994
Předmět:
Zdroj: Pharmacopsychiatry. 27:27-31
ISSN: 1439-0795
0176-3679
DOI: 10.1055/s-2007-1014270
Popis: We investigated the rate of release of seven commercial lithium preparations designated as sustained-release preparations and available in Europe and the USA. The examined products release lithium completely within four hours. The rate of liberation from three drugs resembles that of nonsustained-release preparations, three of which were tested under the same conditions. In one case, the comparison between two batches of sustained-release preparations reveals marked differences in quality. Physicians should be aware that some drugs available on the market and designated as sustained-release preparations do not comply with the international standard for this type of formulation.
Databáze: OpenAIRE