Liberation of Lithium from Sustained Release Preparations
Autor: | Müller-Oerlinghausen B, Heim W, Oelschläger H, Kreuter J |
---|---|
Rok vydání: | 1994 |
Předmět: | |
Zdroj: | Pharmacopsychiatry. 27:27-31 |
ISSN: | 1439-0795 0176-3679 |
DOI: | 10.1055/s-2007-1014270 |
Popis: | We investigated the rate of release of seven commercial lithium preparations designated as sustained-release preparations and available in Europe and the USA. The examined products release lithium completely within four hours. The rate of liberation from three drugs resembles that of nonsustained-release preparations, three of which were tested under the same conditions. In one case, the comparison between two batches of sustained-release preparations reveals marked differences in quality. Physicians should be aware that some drugs available on the market and designated as sustained-release preparations do not comply with the international standard for this type of formulation. |
Databáze: | OpenAIRE |
Externí odkaz: |