Effects of Fullerenol C60(OH)24 on Erythropoiesis in Vitro
| Autor: | Yu. V. Arkhipenko, T. G. Sazontova, N. V. Trofimova, Yu. M. Zakharov, O. L. Kolesnikov, N V Tishevskaya, E. V. Golubotovskii |
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| Rok vydání: | 2014 |
| Předmět: |
geography
geography.geographical_feature_category Chemistry hemic and immune systems General Medicine Islet Molecular biology General Biochemistry Genetics and Molecular Biology In vitro medicine.anatomical_structure Erythroblast hemic and lymphatic diseases Immunology medicine Erythropoiesis Bone marrow circulatory and respiratory physiology |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 157:49-51 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-014-2489-x |
| Popis: | The effects of fullerenol C60(OH)24 in doses of 0.1-100 μg/ml on erythropoiesis were studied in the culture of erythroblastic islets of the bone marrow. Fullerenol in concentrations of 10 and 100 μg/ml had negative effects on the development of erythroid tissue: it inhibits proliferation of erythroid cells, delays erythroblast maturation, decelerates recruitment of erythroid CFU to differentiation, and suppresses repeated involvement of macrophages in erythroblastic islets. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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