Behavioral Changes and Survival in Drosophila melanogaster: Effects of Ascorbic Acid, Taurine, and Caffeine
| Autor: | Hyung Joo Suh, Byungsoo Shin, Ki Bae Hong, Moon Jea Woo, Sung Hee Han |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Vitamin medicine.medical_specialty Taurine Pharmaceutical Science Oxidative phosphorylation 03 medical and health sciences Ingredient chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Pharmacology chemistry.chemical_classification biology Chemistry General Medicine Ascorbic acid Enzyme assay 030104 developmental biology Endocrinology Enzyme Biochemistry biology.protein Caffeine 030217 neurology & neurosurgery |
| Zdroj: | Biological & Pharmaceutical Bulletin. 40:1873-1882 |
| ISSN: | 1347-5215 0918-6158 |
| DOI: | 10.1248/bpb.b17-00321 |
| Popis: | In this study, we used Drosophila as a model species to examine the effects of vitamin or energy-drink and theses ingredients on behavioral activity, life-span, and survivorship. Behavioral assays were performed to analyze total activity during the subjective daytime and nighttime and the lifespan assay was performed to investigate the influence of the drink ingredients. Quantitative RT-PCR and enzyme activity analyses were applied to analyze the mutual relationship of neural pathways and anti-oxidant activities. Caffeine and taurine treatments resulted in significant differences between the control and ascorbic acid groups with respect to subjective daytime and nighttime activity (p |
| Databáze: | OpenAIRE |
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